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Search Results for " retinal permeability "

6

Compounds

Cat No. Product Name Synonyms Targets
T5194 SPHINX31 Serine/threonin kinase
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
T71722 Angiogenesis inhibitor BT2
Angiogenesis inhibitor BT2 is a novel inhibitor of angiogenesis and vascular permeability, inhibiting ERK phosphorylation and the expression of FosB/ΔFosB, VCAM-1, and many genes involved in proliferation, migration, ang...
T35889 PB2
PB2, a tris(2-carboxyethyl)phosphine (TCEP) analogue, enhances the survival of retinal ganglion cells (RGCs) following axotomy in vitro. Even at nanomolar and picomolar concentrations, PB2 demonstrates pronounced efficac...
T61604 PKC-IN-4
PKC-IN-4 (compound 7l) is a highly potent and orally active inhibitor of atypical protein kinase C (aPKC), exhibiting an IC 50 value of 0.52 μM. In vitro studies have demonstrated that PKC-IN-4 effectively suppresses NF-...
T35888 PB1
PB1 is a highly-effective intracellular disulfide reducing agent with notable attributes such as excellent cell permeability, the capacity to generate a substantial intracellular concentration gradient, and remarkable st...
T76895 Abicipar pegol
Abicipar pegol (AGN-150998, MP0112), an anti-VEGF DARPin molecule, represents a novel class of small ankyrin repeat domain-containing proteins designed for high specificity and affinity targeting. This compound is adept ...
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